Upper resp disease + lower resp disease, + glomerulonephritis
Other signs of vasculitis on skin,eyes, joints etc
Best initial: c-ANCA
most accurate test: biopsy
(lung biopsy best)
Tmt: Prednisone +cyclophosphamide.
note: Good pasture has similar presentation but no upper resp involvement and anti GBM abs r present (Best initial test).
kidney biopsy shows linear deposits. No signs of systemic vasculitis unlike in Wegener's granulomatosis.