Wednesday, May 9, 2012

Treatment of inflammatory bowel disease

Acute exacerbations: steroids

Chronic maintenance: mesalamine
note: mesalamine is an active  metaboliteof sulfasalazine. Sulfasalazine was previously used but stopped due to side effects (agranulocytosis, hypospermia) from its other metabolite sulfapyridine.

For perianal disease, give ciprofloxacin+metronidazole
Colectomy can cure UC but is not routine tmt.
Crohn's usually recurs at surgery site

P.S :
IBD serology-  ASk Crohn ANd Call it !
ASCA- Crohn
ANCA- Colitis (ulcerative colitis)  specifically p-ANCA

pronounce the underlined as one sentence.

Most accurate test however is endoscopy

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