interlobular bile duct destruction
itchy, yellow, middle aged woman with high alkaline phosphatase, normal transaminases, high GGT, high bilirubin and positive Anti mitochondrial antibodies, ANA
+signs of cirrhosis
Liver biopsy shows periductal mononuclear infilterate with bile duct destruction
Tmt: Ursodeoxycholic acid, cholestyramine (reduces itching)
no cure
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