Wednesday, May 2, 2012

SIADH

Syndrome of inappropriate ADH secretion.
Too much ADH
Too little urine (anti diuretic), highly concentrated urine, reabsorbing too much water, too dilute plasma
Hyponatremia

Causes:
Look out for CNS diseases (CNS tumour, trauma, stroke etc),chronic Lung diseases (Lung tumour, TB) or medications (vincristine, vinblastine)

Tmt:
Treat primary cause
Ristrict water

If no response, induce nephrogenic DI with Lithium or Demeclocycline.

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