Monday, May 14, 2012

ITP or TTP?

Immune Thrombocytopenic Purpura:
Isolated thrombocytopenia, no hemolysis, normal red cell morphology
Tmt: first line is steroids


Thrombotic Thrombocytopenic purpura:
Microangiopathy due to narrowing of small vessels by thrombus
Thrombocytopenia, fragmented rbcs, schistocytes, neurological symptoms.
Tmt: plasmapheresis

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